Role of anterior commissure in the formation of mirror focus during experimental temporal lobe epilepsy.

In this study the role of anterior commissure was explained in the formation of secondary mirror focus during experimental temporal lobe epilepsy. The experiments were conducted on 12 adult male rabbits. Metallic cobalt powder was implanted unilaterally into basal amygdala as an epileptogenic agent. For the EEG recording bipolar electrodes of insulated nichrome wire were implanted into basal, medial and cortical amygdala, dorsal hippocampus, cortex and ventromedial hypothalamus. For each rabbit 2 recording sessions were held with a 15-channels electroencephalograph. First session was held on the 5th day after cobalt implantation (before the anterior commissure coagulation). Second session was held on the 2nd, 7th, 14th, 22nd and 27th day after anterior commissure coagulation. On the basis of results obtained it was concluded that the electrolytic destruction of only interamygdaloid anatomical connections does not arrest but delays the secondary focus formation (JPMA 30:244, 1980).